Eurasian Medical Research Periodical <p><strong>Eurasian Medical Research Periodical (EMRP</strong><strong>)</strong> is an Open Access, Peer Reviewed, International, Refereed, Scientific Journal that publishes original research and review articles related to diverse areas of Medical Research Advancements etc.</p> <p>The main objective of <strong>Eurasian Medical Research Periodical (EMRP) is</strong> to offer an intellectual platform to the international scholars and it aims to promote interdisciplinary studies in Medical field. All manuscripts must be prepared in English language and subject to a rigorous peer-review process. The scope of the journal is not limited to Bioethics, Chronic non-communicable diseases (NCDs), Climate change, Deafness and other communication disorders, Eye disease, vision health and blindness, Global health security, Household air pollution., Implementation science etc.</p> <p><strong>ISSN (E):</strong> 2795-7624</p> <p><strong>Journal Impact Factor:</strong> 8.120</p> en-US Mon, 08 May 2023 06:44:45 +0000 OJS 60 Cognitive Disorders in Children with Cerebral Palsy <p>Diagnosis of cognitive disorders in children with cerebral palsy is a difficult task due to the diverse combination with motor, speech and sensory pathology, and therefore requires a differentiated approach. The authors have developed differential diagnostic criteria for distinguishing between mental retardation and mental retardation in children with cerebral palsy. The proposed comprehensive system for the rehabilitation of cognitive disorders includes medical-social and psychological-pedagogical correction and is aimed at compensating for cognitive deficits, developing mental functions, and restoring the mechanisms of social integration in children with cerebral palsy.</p> Karimova Dilobar Copyright (c) 2023 Fri, 05 May 2023 00:00:00 +0000 Errors and Exceptions in Endodontic Exercises <p>The article discussed in details the factors affecting the success or failure of endodontic treatment, the protocol of root canal irrigation is given, endodontic treatment errors are analyzed.</p> Kholboeva Nasiba Asrorovna, Abdusattorova Gulbakhor Nazarovna, Mamatov Hamid Boymurod ugli, Asatbayev Jaloliddin Asliddin ugli Copyright (c) 2023 Sat, 06 May 2023 00:00:00 +0000 Improvements Prediction of The Severity of the Clinical Course of Pаrhodonites in Patients with Hypertension <p>The main task of diagnostics is to identify pathology at the earliest possible stages of its development, before the appearance of severe forms and complications. However, given the low awareness of the population and the long-term chronic course of periodontal diseases, patients with advanced periodontitis at a severe stage seek treatment. In these conditions, individual assessment and prediction of the risk of periodontitis in patients with arterial hypertension is relevant. Such studies will serve as a basis for identifying patients with a high risk of developing periodontal diseases, grouping them for the purpose of dental monitoring and implementing measures to neutralize the negative effects of periodontal diseases on the course of hypertension.</p> Muratova Saodat Kadirovna, Teshayev Shoxjahon Otabek o’g’li Copyright (c) 2023 Sat, 06 May 2023 00:00:00 +0000 Modern Approach to The Treatment of Chronic Generalized Periodontitis <p>The article provides modern data on the problem of etiology, pathogenesis, clinical picture and treatment of generalized periodontitis. The authors came to the conclusion that treatment should be comprehensive and aimed at eliminating inflammation in the periodontal area, eliminating the periodontal pocket, stimulating reparative osteogenesis, restoring function, and preventing negative effects on the general health and quality of life of patients. The use of conductors in drugs for the treatment of inflammatory and destructive periodontal diseases is due to their ability to increase the transmucous conductivity of drugs to the inflammation focus, allowing you to create an effective concentration of the active drug component that is part of the composition in the entire volume of periodontal lesions and maintain it throughout the entire period of treatment.</p> Shukurova Nodira Tillayevna, Teshayev Shoxjahon Copyright (c) 2023 Sat, 06 May 2023 00:00:00 +0000 Results of Complex Treatment of Chronic Disseminated Periodontitis in Patients Who Have Undergone Covid-19 <p>In recent times, the primary cause of patients seeking a dentist is paradont disease, leading to premature teeth clots, decreased quality of life due to bad breath, bleeding gums, and dental hyperesthesia. Based on the study, the results of the treatment of 112 patients examined from 2019 to 2022 were included in the orthopedic dentistry department of the Samarkand Regional Dental Department. According to the results of our study, chronic diffuse periodontitis was observed more in the group of patients aged 30-39 years – 39 (34.8%) patients. In chronic diffuse periodontitis, a clear clinical effect was obtained when the Prozone device was applied with a special disposable Period tip in the equivalent of 18 seconds, when the periodontal pockets were applied in combination with an ozonized solution of hypochlorite sodium. Index performance was two times lower. Cytobacterioscopic data prove that inflammation has decreased and eliminated throughout the year</p> Muratova Saodat Kadirovna, Yukimurodov Nurzod Otabek ugli, Absalamov Dilmurod Otamurod ugli Copyright (c) 2023 Sat, 06 May 2023 00:00:00 +0000 A Literary Review of Statistical Indicators in the Diagnosis of Oral Tuberculosis <p>On the basis of statistical diagnostic indicators, the spread of tuberculosis among the world's population was studied. The data obtained will help improve the early diagnosis of patients with active tuberculosis and their provision of planned dental care</p> Muratova Saodat Kadirovna, Shukurova Nodira Tillayevna Copyright (c) 2023 Sat, 06 May 2023 00:00:00 +0000 Endodontic Treatment of Chronic Apical Periodontitis with The Drug Hydroxy calcium by Delayed Filling <p>Treatment of patients with chronic periodontitis is one of the most difficult and important tasks of modern dentistry. 134 patients were examined on an outpatient basis with endodontic treatment of the two most common types of pastes: resorcinol-formalin and Calcevit. According to the type of paste, all examined patients were divided into two groups: 78 patients (51.5%) whose teeth were sealed with resorcinol-formalin paste and 56 patients (48.5%) with Calcite paste. According to the results of the study, it was found that in the group of teeth previously treated with resorcinol-formalin paste, more than 2/3 were molars (77.0 + 2.2%), every fifth tooth was premolar (19.1 + 2.0%) and there were fewer front teeth (3.9 + 1.0%). In the group of teeth previously treated with Calcite paste, the ratio of types of teeth in different age subgroups differed. Almost equal proportions in frequency were noted for the anterior teeth (29.2 + 2.4%), premolars (29.8 + 2.4%), the proportion of molars was slightly higher (41.0 + 2.4%).</p> Muratova Saodat Kadirovna, Naimov Sadridin Sirozhitdin ugli, Toshtemirov Islom Chori ugli Copyright (c) 2023 Sat, 06 May 2023 00:00:00 +0000 Structural Changes of Internal Organs in Experimental Purulent Peritonitis <p>The structure of the intestine’s wall. liver and heart were studied in acute peritonitis and postoperative period. The experiment was performed on 25 male rabbits. Morphological changes were investigated using light microscopy with haematoxylin-eosin and Van Gison staining. It was shown that the development of acute peritonitis led to significant changes in the intestine. liver and heart. Inflammatory reaction with predominance of exudation was combined with dystrophic alteration in described organs. The changes arose towards the first day and lowered by the fifth day of postoperative period when regeneration processes developed.</p> Suleymanov R.I, Kiyamov B.E, Kamalova M. I. Copyright (c) 2023 Sat, 06 May 2023 00:00:00 +0000 Diagnostic Possibilities of Ultrasound in Polycystosis of the Kidney <p>The article presents the results of examination of 4 patients suffering from polycystic kidney disease. It is noted that ultrasound methods are the most informative in the diagnosis of this pathology. The clinical course of polycystic disease was characterized by few symptoms . Despite the severity of morphological changes, kidney function suffered slightly. The possibility of dynamic changes in the size and content of cysts throughout life is assumed , as well as the presence of a congenital connective tissue defect in familial polycystic kidney disease.</p> Xojirahmatov Davron Copyright (c) 2023 Sat, 06 May 2023 00:00:00 +0000 Alberuni Opinion about history of biology (Darwinism and Evolution A second document) <p>Abu-Alraihan Muhammad Ibn Ahamad Alberuni (362-440Ah , 973-1048 AD) an Arabic Moslem philosopher , astronomer , mathematician ,pharmacist and biology historian . His opinion about history of biology was expressed in one of the many books and treatises that he wrote which was translated to English language ; History of India . It was some 60-70 years ago when T.I.Rainow(1943) called attention to the fact that in this book India , his thoughts about natural selection , through struggle for life and survival of the fittest was expounded. Jan Z.Wilczynski (1959) published a paper about this presumed Darwinism of Alberuni as was expressed in his book India</p> Dr. Radhi Jawad Bakir Al- Bayati Copyright (c) 2023 Sat, 06 May 2023 00:00:00 +0000 Еssential Factors Of Etiopathogenesis In The Development Of Parodontal Diseases In Post-Menopasis Women <p>The structure of the intestine’s wall. liver and heart were studied in acute peritonitis and postoperative period. The experiment was performed on 25 male rabbits. Morphological changes were investigated using light microscopy with haematoxylin-eosin and Van Gison staining. It was shown that the development of acute peritonitis led to significant changes in the intestine. liver and heart. Inflammatory reaction with predominance of exudation was combined with dystrophic alteration in described organs. The changes arose towards the first day and lowered by the fifth day of postoperative period when regeneration processes developed.</p> Islamova Nilufar Bustonovna, Nazarova Nodira Sharipovna Copyright (c) 2023 Wed, 10 May 2023 00:00:00 +0000 Some Morphological Changes in the Structure of the Heart <p>The aim of our work is to identify features of morphogenesis in postnatal development, the study of the histological structure of different departments and membranes of rat heart at 1-22 days after birth. The object of the study was the heart of the 50 rats at 1, 6, 11, 16, 22 days after birth. Notes alternating periods of acceleration and deceleration of the growth rate increasing thickness of the atria and ventricles. Endocardial and epicardial thickness increases significantly less. The growth rate of the thickness of the ventricular myocardium were observed in rats 6 and 16 days of age. Structural changes occur due to the growth of the organism. Feature of the structure and topography of microvessels heart is their distribution in the course of cardiomyocytes and the relationship with fibrous connective tissue structures of cardiomyocytes.</p> Mirsharopov U.M, Abdikadirov Sh.I., Akhmedova S.M. Copyright (c) 2023 Wed, 10 May 2023 00:00:00 +0000 Vascular of the Heart of Rats Under the Influence of Pesticides <p>The analysis of morphological and morphometric changes under the influence of pesticides on off spring of rats in the early postnatal ontogenesis passed through the mother's milk was made. Under the influence of pesticides, wall thickness of atrium and ventricles of all ages is reduced as compared with the control group. There is a reactive change in the vessels in the form of expansion and plethora, development of perivascular edema and diapedetic hemorrhage. In our opinion, this leads to disruption of the functional activity of the myocardium, eventually to the emergence of degenerative disorders in many organs and systems.</p> Akhmedova S. M, Abdikadirov Sh. I, Sagdullaeva M.K Copyright (c) 2023 Fri, 12 May 2023 00:00:00 +0000 Features of the Formation of the Heart Wall in Early Postnatal Ontogenesis <p>In order to identify the features of morphogenesis in postnatal ontogenesis examined histological structure of different departments and shells in the heart of rats 1-22 days after birth. There alternating periods of acceleration and deceleration of the growth rate increase in the thickness of the atrium and the ventricles. The thickness of the endocardial and epicardial increases less significantly. The growth rate of the ventricular myocardium thickness observed in rats 6 and 16 days of age. Structural changes occur due to the growth of the organism. A special feature of the structure and topography of the heart microvessels is their distribution in the course of the cardiomyocytes and the relationship with the fibrous structures of the connective tissue of cardiomyocytes.</p> Abdikadirov Sh.I., Akhmedova S.M, Nisabayeva A.U. Copyright (c) 2023 Fri, 12 May 2023 00:00:00 +0000 Improvement of Methods for the Prevention of Obstetric Complications in Women with Fetus Macrosomia <p>Fetal macrosomia is associated with significant maternal and neonatal morbidity. In the long term, infants who are large for gestational age are more likely than other infants to be obese in childhood, adolescence and early adulthood, and are inherently at higher risk of cardiovascular and metabolic complications in adulthood. With over one billion adults in the world now overweight and more than 600 million clinically obese, preventing the vicious cycle effect of fetal macrosomia and childhood obesity is an increasingly pertinent issue. Fetal growth is determined by a complex interplay of various genetic and environmental influences. Consequently the prediction of pregnancies at risk of pathological overgrowth is difficult. Many risk factors for fetal macrosomia, such as maternal obesity and advanced maternal age, are also conversely associated with intrauterine growth restriction. Sonographic detection of fetal macrosomia is notoriously fraught with difficulties, with dozens of formulas for estimated fetal weight proposed but few with sufficient sensitivity to alter clinical practice.</p> Yuldasheva Dilchekhra Yusufkhanovna, Uktamova Gavkhar Tolibovna Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 Evaluation Of Medicinal Properties Of Chestnut Fruit Used In The Treatment Of Varicose Diseases By Chemical Composition <p>The article provides information on the importance of vitamins used in the treatment of varicose veins, and the determination of the amount of water-soluble vitamins in an aqueous extract of chestnut fruits using the "High-Performance Liquid Chromatography" method.</p> Madaminova Gulassal Abdurauf qizi, Xojiqulov Azizbek Sobirovich, Asqarov Ibrohim Rahmonovich Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 Clinical Aspects of the Combined Course of Pulmonary Tuberculosis and Type 2 Diabetes Mellitus <p>The results of a comparative analysis of 80 cases of patients with chronic obstructive pulmonary disease (COPD) are considered: 40 cases with comorbid pathology (COPD and type 2 diabetes mellitus (DM)) and 40 cases of COPD without type 2 diabetes. The data of questionnaires, tests, clinical laboratory and instrumental indicators were analyzed. The negative role of type 2 diabetes on the course of COPD was demonstrated by such indicators as the frequency of exacerbation of COPD per year, the frequency of calls to ambulance teams, the frequency of hospitalizations due to exacerbation or worsening of the course of COPD, clinical symptoms of COPD, spirometry parameters, and indicators of cytokine and adipocytokine profiles.</p> Batirova Barchinoy Tadjimukhammedovna Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 The Course of Tuberculosis in Elderly Patients with Comorbid Background <p>Pulmonary tuberculosis often develops against the background of diseases that lead to dysfunction of organs and systems, and in a joint course, they have a mutually aggravating interaction. This complicates the timely diagnosis of tuberculosis, and in the treatment entails forced polypharmacy, the development of drug complications and failures in treatment.</p> Oripov Shavkat Yuldashevich Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 Therapy Of Post-Covid Fibrotic Changes <p>Among the extensive manifestations of post-covid syndrome, cough is often found. Most researchers interpret its nature as post-infectious. In some patients, postinfectious cough becomes productive and effective treatment requires combined mucoactive therapy. Also, since the beginning of the pandemic, enough clinical observations of spontaneous pneumothorax have accumulated in the literature. The risk of this complication is present even in patients who are not burdened with chronic lung diseases, as well as in spontaneous breathing. The study of the mechanisms of development of spontaneous pneumothorax in COVID-19 is necessary for the development of further therapeutic and preventive measures. Traction bronchiectasis occurs in 27–52.5% of cases of novel coronavirus infection (NCI).</p> Abdumanapova Rano Kakhramanovna Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 The Course Of Pregnancy And Childbirth In Women With Varying Degrees Of Anemia, Suffering From Pulmonary Tuberculosis. <p>In this given article you can find out the course of tuberculosis in pregnant women with varying degrees of anemia, the effectiveness of traditional drugs, herbal preparations.</p> Khakimova Roza Abdurahimovna Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 Pathogenesis, Diagnostics and Treatment Effectiveness of Posthemorrhagic Iron Deficiency Anemia with Thrombocytopenia, (Werlhoff's Disease) <p>With thrombocytopenic purpura, there is a violation of the formation of thromboplastin and serotonin, a decrease in contractility and an increase in the permeability of the capillary wall. This is associated with prolongation of bleeding time, violation of the processes of thrombosis and retraction of the blood clot. With hemorrhagic exacerbations, the number of platelets decreases down to single cells in the preparation, during the period of remission it is restored to a level below the norm</p> Akhmadjonov Ravshanbek Sodikovich, Yuldasheva Nodira Ergashevna Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 Pathogenetic and Combined Treatment of Iron Deficiency Anemia with Drugs Increasing Erythropoiesis <p>An increase in the amount of iron in the body leads to stimulation of the synthesis of hepcidin, which reduces iron absorption in the intestine, transport and circulation. In turn, a decrease in iron absorption in the intestine leads to inhibition of hepcidin synthesis in the liver and, in feedback, to the restoration of iron uptake from food and intestines. So far, antibodies against hepcidin have not been obtained and it is not possible to measure its level in a clinical setting. Work in this direction is underway.</p> Gulshanoi Akmaljonovna Karimkulova, Yuldasheva Nodira Ergashevna Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 Complications Of Secondary Immunodeficiency, Diagnosis and Treatment of Leukopenia in Patients with Acute Leukemia <p>The characteristic manifestations of NL are intracranial hypertension, meningeal syndrome, and cytosis in the cerebrospinal fluid. However, on the one hand, there has not yet been an idea of the course of NL with modern tactics for the treatment of acute hemoblastoses, on the other hand, the appearance of even reduced neurological symptoms significantly worsens the clinical course of the disease, aggravates the prognosis and requires an immediate change in the tactics of therapy</p> Shakhobidinov Nohidbek Vohidjon ugli, Yuldasheva Nodira Ergashevna Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 Anemic Syndrome In Chronic Diseases <p>Diagnosis of chronic active hepatitis - study of liver function tests, serum markers of hepatitis viruses, immunological parameters, determination of antibodies to antigens, ultrasound and liver biopsy; rheumatoid arthritis - X-ray of the joints, a blood test for rheumatoid factor, for antibodies to citrullinated peptide and citrullinated vimentin; seronegative arthritis - X-ray of the joints of the lumbosacral spine, sacroiliac joints, a study for chlamydial infection, a blood test for rheumatoid factor. To diagnose tuberculosis of various localizations, x-rays and tomography of the lungs are performed, sputum and bronchial washings are examined, and a nephrourological examination with urinalysis, ultrasound is performed, X-ray methods are used (for tuberculosis of the kidneys and urinary system), an examination is prescribed by a urologist and gynecologist (for urogenital -tal tuberculosis).</p> Boltiboeva Zulaikho Komiljon qizi, Yuldasheva Nodira Ergashevna Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 CT Imaging Diagnosis in Ovarian Cancer <p>Ovarian cancer is a significant health concern, and early detection and accurate diagnosis are crucial for improving outcomes and survival rates. CT imaging is a widely used diagnostic tool in ovarian cancer, with the ability to detect lesions and evaluate disease extent. In this review essay, we explore the role of CT imaging in the diagnosis of ovarian cancer, including its benefits and limitations. We discuss the potential impact of CT imaging on patient care and highlight the importance of integrating this diagnostic tool into clinical practice. Our findings suggest that CT imaging can play a valuable role in the early detection and diagnosis of ovarian cancer, and we recommend further research to optimize its use in clinical practice.</p> Norqizilova.G.O, Ismailova.M.Kh, Xayitboyeva.M.R, Alisherova. M.A, Valiyev. Y.Y., Tairova M.I. Copyright (c) 2023 Sat, 13 May 2023 00:00:00 +0000 Morph Functional Changes of Ferments in the Neutrophiliac of Peripheral Blood in the Case of Virus Hepatitis B at Children <p>The activity of SDG, LDG, G-6-FDG and £-GFDG at ill children has been studied. The change of ferments activity in depending of VHB course heaviness has been investigated. Steady and deep lowering of dehydrogenizes activity was marked at 6 patients (6,8%) with fulminant form of VHB. It was concluded that t VHB the aerobic way of carbohydrate transformation (SDG) is sharply disordered, β-glycerol phosphate (β-GFD) and peptone phosphate (G-β-FDG) bypasses are suffered, as well as glycolysis (LDG) is activated. It is evidence of acute changes in energy phenomena, leading to the gathering of lactate and metabolic acidosis. Steady lowering of dehydro genesis is prognostically unfavorable indicator of VHB course.</p> Xakimova Iqbolxon Tursunbayevna Copyright (c) 2023 Sat, 20 May 2023 00:00:00 +0000 Clinics and Peculiarities of the Course of Combined Viral Hepatitis <p>Conducted clinical and serologic examination of 1400 children aged 0-14 with acute viral hepatitis in order to reveal the etiology of hepatitis and the number of combined forms among them was performed. During our investigation we revealed some peculiarities in clinical course, clinical symptoms and aggravation of the disease in case of combined course of VHB and VHC. In case of combination of AVHA+AVHB and AVHA associated with HBSAg significant prolongation of remission was noted. Among 294 patients with A VHB acute delta-viral infection was revealed in 51 persons. It gave the possibility to determine some clinical peculiarities and differentiations of VHD in case of co - infection and super infection. The obtained data allows to prognosticate frequency of different forms of VH in the region and help to perform rational measures on decreasing YH morbidity.</p> Axmedova Dildarxon Kabilovna Copyright (c) 2023 Sat, 20 May 2023 00:00:00 +0000 Clinical and Pathogenetic Aspects of Combined Hepatitis "B" And "C" <p>In order to study the issues of pathogenesis, clinic and diagnosis of combined liver lesions with hepatitis B and C viruses, 38 patients with various forms of mixed hepatitis B + C were comprehensively examined. During the infectious process of combined HBV/HCV etiology, indirect signs of mutual inhibition of two hepatotropic viruses were observed. The severity of clinical, laboratory and histological changes in the liver in latent forms is mainly due to HCV infection; it is characterized by the rapidity of HBeAg/HBeAb seroconversion and the disappearance of HBV DNA from the patient's blood against the background of ongoing HCV persistence. Isolation of various variants of the course of mixed hepatitis is uninformative in relation to the outcome and prognosis of the disease. At the same time, a thorough assessment of the activity of viral replication of both pathogens determines the choice of rational therapy.</p> Vakkasova Muazzamxon Kabulovna Copyright (c) 2023 Sat, 20 May 2023 00:00:00 +0000 Uniqueness of New Modern Methods of Diagnosing Tuberculosis <p>Differential diagnosis of the etiology of phthisis is an urgent problem in phthisiology. The study made it possible to establish, for the purpose of differential diagnosis of leaks, to establish tuberculous etiology, in addition to traditional research methods, use Diaskintest [out of 24, 16 (66.6%) gives a positive result], in patients with a negative and dubious Mantoux test. The performed analysis of discharge from the congestion using the GeneXpert Rif method in patients with a negative smear result by bacterioscopy in 53.5% allows us to detect tuberculosis, and patients with drug-resistant tuberculosis begin adequate complex therapy. The most frequently aggravated complications were tuberculous spondylitis in 34 patients with coxitis in 12 patients and tuberculosis of peripheral lymph nodes in 11 patients.</p> Batirova BarchinoyTajimuxammadovna Copyright (c) 2023 Sat, 20 May 2023 00:00:00 +0000 Characteristics And Effects Of Acute Bronchiolitis In Infectious Children (Citomegalovirus) <p>The article is dedicated to the problem of acute bronchitis in children. The relevance of this problem is obvious: according to conservative estimates, more than 150 million cases of bronchiolitis are registered annually.7-13% of these cases require hospital treatment and 1-3%-hospitalization in an ICU. The most common etiologic factor is the virus-respiratory synsytial (the vast majority of cases-60- 80%)cytomegalovirus, influenza viruses, parainfluenza, adenovirus, coronavirus are also important agents. A number of factors can cause the evolution of bronchiolitis in 0- 2 years-old children. Premature infants, children with bronchopulmonarydysplasia, bottle-fed children, and patients with congenital malformations and immunodeficiencies undergo bronchiolitis especially hard</p> Isanova Dilfuza Tursunovna Copyright (c) 2023 Sat, 20 May 2023 00:00:00 +0000 Clinical Effectiveness Of Psychopharmacotherapy Of Neurotic Disorders In Psoriasis <p>On the basis of the Republican Specialized Scientific and Practical Medical Center for Dermatology and Venereology of the Ministry of Health of the Republic of Uzbekistan, later in the department of the Fergana Regional Dermatology and Venereal Diseases Dispensary No. 2 in the city of Kokand, as well as in the departments of the Fergana Regional Dermatology and Venereal Diseases Dispensary No. 1 in the city of Fergana, 100 patients with psoriasis (men - 60 people, women - 40 people) aged 18 to 72 years were examined. Based on the results of the study, the article discusses the issues of studying the significance of psychotherapeutic and psychopharmacotherapeutic treatment of neurotic disorders in patients with various forms of psoriasis, which will significantly increase the therapeutic effectiveness of the methods of therapy used, as well as lengthen the terms of clinical remission, which will be reflected in the quality of life of patients.</p> Agranovsky Mark Lazarevich, Rakhmatov Akram Baratovich, Makhmutov Rustam Khamitovich Copyright (c) 2023 Sat, 20 May 2023 00:00:00 +0000 To determine the prevalence and improve the effectiveness treatment of dental diseases in patients with COVID-19. <p>The article presents the results of a study of the state of local immunity in the oral cavity in 30 patients with COVID-19, depending on the severity</p> F.U. Jabbarova Copyright (c) 2023 Wed, 24 May 2023 00:00:00 +0000 Relationship between body mass index and gastroesophageal reflux disease in Mosul City <p>The gastro-esophageal reflux disease (GERD) considered as a diagnostic and therapeutic challenge. Its incidence is increasing parallel with obesity worldwide. This study tried to find a correlation between the disease and body mass index (BMI).</p> Waleed Khalid Mohammed Alhamoud, Noori Tauma Mahmood Copyright (c) 2023 Sat, 20 May 2023 00:00:00 +0000 Prevalence of helicobacter pylori infection in children (Prospective study) <p>The current guidelines for eliminating Helicobacter pylori (H. pylori) in adults vary from those for children. infected with H. pylori should always seek treatment to eliminate the infection. as a result of the possibility of contracting infections outside of the digestive system. Instead of focusing just on H. pylori infection, we should evaluate all potential reasons before treating affected infants. In fact, the test-and-treat approach is not recommended for kids according to worldwide pediatric standards. Therefore, in order to properly analyse all of the potential causes of the symptomatology and to enhance the eradication rate, gastroscopy with antimicrobial susceptibility testing by culture on stomach biopsies should be conducted before to beginning the eradication therapy in children. If antibiotic susceptibility testing is unavailable, gastroscopy is nevertheless advised in order to determine the true source of any symptoms rather than only looking for H. pylori. Because there aren't as many antibiotics available for kids as there are for adults, doctors sometimes resort to antimicrobial susceptibility testing to cut down on treatment failures. Amoxicillin, clarithromycin, and metronidazole, in various combinations, are the principal antibiotics prescribed for children. When treating an infection without first determining its antimicrobial susceptibility, it is common practice to use a 14-day course of triple therapy. In cases of double-resistance or as a secondary therapeutic option, triple therapy with a high dose of amoxicillin is an option worth considering. From there, we might choose quadruple treatment with or without bismuth salts, which is based on therapeutic regimens typically administered to adults. Unfortunately, many children are less compliant with treatment regimens because of the severe side effects they may experience. This analysis also takes a look at several alternatives to standard pediatric care that are gaining popularity</p> Dr. Muwafaq M.Younes H.Mosa, Dr. Abbas Mohsin Younus, Dr.Omar Saad Tawfeek Copyright (c) 2023 Mon, 22 May 2023 00:00:00 +0000